Carbamic chloride → HCID 86707922, compound

HRID 514748Notes

Reaction equation

HRID 514748 reaction equation
[CH2:1]([NH:8][CH2:9][CH2:10][O:11][CH2:12][CH2:13][O:14][CH2:15][CH2:16][O:17][C:18]#[C:19][CH3:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:21]([Cl:24])(=[O:23])N>>[CH2:1]([N:8]([CH2:9][CH2:10][O:11][CH2:12][CH2:13][O:14][CH2:15][CH2:16][O:17][C:18]#[C:19][CH3:20])[C:21]([Cl:24])=[O:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 68048Carbamic chlorideHCID 86707923HCID 86707923, compound

Product 1

HCID 86707922HCID 86707922, compound

Procedure

N-Benzyl-2-(2-(2-(propynyloxy)ethoxy)ethoxy)ethyl aminocarbonyl chloride was prepared from amine 27 (20 mg, 0.072 mmol) following General Procedure 1. The crude carbamoyl chloride was used directly for the next step.

Sources & evidence

ORD record
ord-3001334b82df4fe38fb9fdc78d4cc755
Source dataset
uspto-grants-2015_08
Patent number
US09108930B2

Reaction notes

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