反应详情

To a round bottom flask was added benzyl-4-(benzyloxymethoxy)-4-(2-fluoro-2-methylpropyl)piperidine-1-carboxylate (50 mg, 0.12 mmol), Pd/C (20 mg), and methanol (5 mL). The mixture was stirred at room temperature for 16 hrs under hydrogen atmosphere. The reaction mixture was filtered to get a solution, which was concentrated to give the desired product. The crude product was used directly for the next step. LC-MS: m/z 176.2 (M+H)+

1. filtrationThe reaction mixture was filtered
2. customto get a solution, which
3. concentrationwas concentrated