2-Methylbenzoic acid → N-[2-(4-Chloro-phenyl)-2-morpholin-4-yl-ethyl]-2-methyl-benzamide

HRID 514927Notes

Reaction equation

HRID 514927 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH:18]([N:21]2[CH2:26][CH2:25][O:24][CH2:23][CH2:22]2)[CH2:19][NH2:20])=[CH:14][CH:13]=1>>[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH:18]([N:21]2[CH2:22][CH2:23][O:24][CH2:25][CH2:26]2)[CH2:19][NH:20][C:4](=[O:6])[C:3]2[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=2[CH3:1])=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 83732-Methylbenzoic acidHCID 164619232-(4-Chlorophenyl)-2-(morpholin-4-yl)ethan-1-amine

Product 1

HCID 52985828N-[2-(4-Chloro-phenyl)-2-morpholin-4-yl-ethyl]-2-methyl-benzamide

Procedure

From 2-methylbenzoic acid and 2-(4-chloro-phenyl)-2-morpholin-4-yl-ethylamine.

Sources & evidence

ORD record
ord-c212c853e8724ba3a56d21c7bde0e344
Source dataset
uspto-grants-2015_08
Patent number
US09108938B2

Reaction notes

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