2-Chloro-3-fluorobenzoic acid → HCID 73672708, compound

HRID 514964Notes

Reaction equation

HRID 514964 reaction equation
[Cl:1][C:2]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[O:12]1[CH2:17][CH2:16][N:15]([CH:18]([C:21]2[CH:22]=[N:23][C:24]([C:27]([F:30])([F:29])[F:28])=[N:25][CH:26]=2)[CH2:19][NH2:20])[CH2:14][CH2:13]1>>[Cl:1][C:2]1[C:10]([F:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:20][CH2:19][CH:18]([N:15]1[CH2:16][CH2:17][O:12][CH2:13][CH2:14]1)[C:21]1[CH:26]=[N:25][C:24]([C:27]([F:29])([F:30])[F:28])=[N:23][CH:22]=1)=[O:6]

Participants

3

Reactant 2

HCID 3026202-Chloro-3-fluorobenzoic acidHCID 468355732-(Morpholin-4-yl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]ethan-1-amine

Product 1

HCID 73672708HCID 73672708, compound

Procedure

From 2-chloro-3-fluorobenzoic acid and 2-morpholino-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethanamine.

Sources & evidence

ORD record
ord-d385a31639e340af8384d81bb18e45a0
Source dataset
uspto-grants-2015_08
Patent number
US09108938B2

Reaction notes

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