4-Fluoro-2-methylphenol → 4-(2-(4-Fluoro-2-methylphenoxy)-4-(perfluoroethyl)benzamido)benzoic acid

HRID 515094Notes

Reaction equation

HRID 515094 reaction equation
F[C:2]1[CH:33]=[C:32]([F:34])[CH:31]=[CH:30][C:3]=1[O:4][C:5]1[CH:22]=[C:21]([C:23]([F:29])([F:28])[C:24]([F:27])([F:26])[F:25])[CH:20]=[CH:19][C:6]=1[C:7]([NH:9][C:10]1[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[CH:12][CH:11]=1)=[O:8].F[C:36]1C=CC(O)=C(C)C=1>>[F:34][C:32]1[CH:31]=[CH:30][C:3]([O:4][C:5]2[CH:22]=[C:21]([C:23]([F:29])([F:28])[C:24]([F:26])([F:27])[F:25])[CH:20]=[CH:19][C:6]=2[C:7]([NH:9][C:10]2[CH:11]=[CH:12][C:13]([C:14]([OH:16])=[O:15])=[CH:17][CH:18]=2)=[O:8])=[C:2]([CH3:36])[CH:33]=1

Participants

3

Reactant 2

HCID 1362954-Fluoro-2-methylphenolHCID 778442634-(2-(2,4-difluorophenoxy)-4-(perfluoroethyl)benzamido)benzoic Acid

Product 1

HCID 778442624-(2-(4-Fluoro-2-methylphenoxy)-4-(perfluoroethyl)benzamido)benzoic acid

Procedure

4-(2-(4-fluoro-2-methylphenoxy)-4-(perfluoroethyl)benzamido)benzoic acid (3) was prepared following a procedure similar to the one reported above for compound 2 from 4-fluoro-2-methylphenol.

Sources & evidence

ORD record
ord-8a5b10b794a141508958c52527f76fbc
Source dataset
uspto-grants-2015_08
Patent number
US09108903B2

Reaction notes

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