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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 515252Generated: October 30, 2026

4-Amino-6-bromo-2-methylpyrimidine → Isopropyl 2-(6-bromo-2-methylpyrimidin-4-ylamino)thiazole-5-formate

https://huagongshe.com/reaction/515252

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-6-bromo-2-methylpyrimidineHCID 56965719—
ReactantIsopropyl 2-chlorothiazole-5-formateHCID 71082669—
ProductIsopropyl 2-(6-bromo-2-methylpyrimidin-4-ylamino)thiazole-5-formateHCID 4982180876.9%

Reaction Steps

Prepared from isopropyl 2-chlorothiazole-5-formate and Compound 9: isopropyl 2-(6-bromo-2-methylpyrimidin-4-ylamino)thiazole-5-formate was yielded (yield: 76.9%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09108954B2
Source datasetuspto-grants-2015_08
ORD IDord-27abd74500c147c79bcd8e6da2ca0dc2
Source noteuspto-grants-2015_08