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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 515264생성일: 2026년 10월 25일

1,1,1,3,3,3-Hexafluoro-2-(4-((4-(4-nitrophenoxy)piperidin-1-yl)methyl)phenyl)propan-2-ol → HCID 86670926, 화합물

https://huagongshe.com/reaction/515264

반응식

참여 물질

역할이름HCID투입량
반응물1,1,1,3,3,3-Hexafluoro-2-(4-((4-(4-nitrophenoxy)piperidin-1-yl)methyl)phenyl)propan-2-olHCID 86670925—
촉매PalladiumHCID 23938—
용매MethanolHCID 887—
생성물HCID 86670926HCID 86670926—

반응 단계

1,1,1,3,3,3-Hexafluoro-2-(4-((4-(4-nitrophenoxy)piperidin-1-yl)methyl)phenyl)propan-2-ol (4.01 mmol, 1.92 g) and palladium (10% on carbon, Degussa) (0.040 mmol, 0.085 g) were hydrogenated in methanol (20 mL) at 5 bar for 1 hour at room temperature. The reaction mixture was filtered and the filtrate concentrated under vacuum to afford the title compound. MS (ESI) m/z 449.1 [M+H]+

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09108939B2
출처 데이터셋uspto-grants-2015_08
ORD IDord-b21252ddc4174d2e83a820f12fa6df18
출처 메모uspto-grants-2015_08