Trifluoroacetic acid → HCID 86670962, compound

Participants

Reaction Steps

A mixture of tert-butyl ethyl(1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)piperidin-4-yl)carbamate (6.61 mmol, 3.2 g), dichloromethane (10 mL) and trifluoroacetic acid (10 mL) was stirred for 20 hours. Purification by SCX chromatography gave the title compound (2.5 g). MS (ESI) m/z 385.1 [M+H]+

Provenance & Evidence