Trifluoroacetic acid → HCID 67193617, compound

Participants

Reaction Steps

2,2,2-Trifluoroacetic acid (1.88 mL, 24.39 mmol) was added to a solution of tert-butyl 4-(4-(3-(cyclopropylmethyl)ureido)-N-methylbenzamido)piperidine-1-carboxylate (420 mg, 0.975 mmol) in dichloromethane (10 mL). The mixture was stirred at ambient temperature for 4 hours and then treated with strong cation exchange column chromatography to afford the title compound (300 mg). MS (ESI) m/z 331.1 [M+H]+

Provenance & Evidence