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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 515373Generated: October 30, 2026

HCID 68610220, compound → HCID 68272183, compound

https://huagongshe.com/reaction/515373

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68610220HCID 68610220—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 68272183HCID 6827218397.9%

Reaction Steps

tert-Butyl 4-(5-nitro-1H-indazol-1-yl)piperidine-1-carboxylate (6.78 mmol, 2.35 g) and 10% palladium on carbon (0.136 mmol, 0.144 g) were combined and stirred in ethanol (50 mL) under 5 bar hydrogen for 1 hour. The reaction mixture was filtered and the filtrate concentrated under vacuum to afford the title compound (2.1 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09108939B2
Source datasetuspto-grants-2015_08
ORD IDord-4c59e53afa734b48b00aa95fb734548f
Source noteuspto-grants-2015_08