Carbamic acid, 4-pyridinyl-, phenyl ester → HCID 86670998, compound

Participants

Reaction Steps

2-(4-((4-(5-Amino-2H-indazol-2-yl)piperidin-1-yl)methyl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol (0.212 mmol, 0.1 g) and phenyl pyridin-4-ylcarbamate (0.318 mmol, 0.068 g) were combined and stirred in dioxane (2 mL) at 100° C. in a Reactivial. The solvent was removed and the resulting residue was purified by silica chromatography (eluting with a solvent gradient from dichloromethane to 8% methanol/dichloromethane) to afford the title compound (14 mg).

Provenance & Evidence