Trifluoroacetic acid → HCID 22611608, compound

Participants

Reaction Steps

tert-Butyl 4-(5-amino-1H-indol-1-yl)piperidine-1-carboxylate (7.95 mmol, 2.506 g) was stirred in tetrahydrofuran (10 mL)/trifluoroacetic acid (10 mL) at room temperature for 1 hour. The solvent was removed at reduced pressure. The resulting residue was passed down an SCX column to afford the title compound (660 mg).

Provenance & Evidence