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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 515535Generated: October 30, 2026

Cyclopropanemethanamine → HCID 118094020, compound

https://huagongshe.com/reaction/515535

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanamineHCID 75646—
ReactantHCID 118094028HCID 118094028—
SolventDimethylformamideHCID 6228—
ProductHCID 118094020HCID 118094020—

Reaction Conditions

Temperature110 °C

Reaction Steps

A mixture of 2-chloro-N-cyclopentyl-7-(3,5-dimethylisoxazol-4-yl)quinoline-5-sulfonamide (23 mg, 0.057 mmol), cyclopropylmethyl amine (0.2 mL) and DMF (0.5 mL) was heated at 110° C. for 1 hour. The reaction mixture was purified by preparative HPLC to give the desired product, N-cyclopentyl-2-((cyclopropylmethyl)amino)-7-(3,5-dimethylisoxazol-4-yl)quinoline-5-sulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09108953B2
Source datasetuspto-grants-2015_08
ORD IDord-855456a9f0424b5aa0d9b0a6bbe4a7d2
Source noteuspto-grants-2015_08