HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 515536Generated: October 30, 2026
Sodium hydride → HCID 118094090, compound
https://huagongshe.com/reaction/515536
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Cyclopropanemethanol | HCID 75644 | — |
| Reactant | HCID 118094028 | HCID 118094028 | — |
| Product | HCID 118094090 | HCID 118094090 | — |
Reaction Steps
A mixture of 2-chloro-N-cyclopentyl-7-(3,5-dimethylisoxazol-4-yl)quinoline-5-sulfonamide (18 mg, 0.044 mmol) and cyclopropylmethanol (1 mL) was treated with excess sodium hydride and heated to 60° C. overnight. The mixture was concentrated and purified by preparative HPLC to give the desired product, N-cyclopentyl-2-(cyclopropylmethoxy)-7-(3,5-dimethylisoxazol-4-yl)quinoline-5-sulfonamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09108953B2 |
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| Source dataset | uspto-grants-2015_08 |
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| ORD ID | ord-5759365e4cc248b0867f54dec9a10f33 |
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| Source note | uspto-grants-2015_08 |
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