HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline → 5-(Pyridin-4-yl)-3,4-dihydroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline | HCID 58416471 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Product | 5-(Pyridin-4-yl)-3,4-dihydroisoquinoline | HCID 89500017 | 80% |
Reaction Steps
Intermediate 17B was oxidized using MnO2. After 24 h, the reaction was filtered through Celite® and concentrated to afford 75 mg (80%) of Intermediate 17 as yellow oil. MS (ESI) m/z: 209.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09108951B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-54bd3cbf9da24179bd49c34162bcd1dd |
| Source note | uspto-grants-2015_08 |