HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-methyl-3-pyrrolecarboxylate → 4-Fluoro-2-[4-(methoxycarbonyl)-1,5-dimethyl-1H-pyrrol-2-yl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-methyl-3-pyrrolecarboxylate | HCID 136747 | — |
| Reactant | 2-Bromo-4-fluorobenzaldehyde | HCID 2773319 | — |
| Reactant | Methyl 2-methyl-1H-pyrrole-3-carboxylate | HCID 12333388 | — |
| Reactant | 2-Bromo-4-chlorobenzaldehyde | HCID 13154710 | — |
| Product | 4-Fluoro-2-[4-(methoxycarbonyl)-1,5-dimethyl-1H-pyrrol-2-yl]benzoic acid | HCID 117833786 | — |
Reaction Steps
The procedure is in accordance with the process of Preparation 1, replacing, in Step A, the ethyl 2-methyl-1H-pyrrole-3-carboxylate by methyl 2-methyl-1H-pyrrole-3-carboxylate and also the 2-bromo-4-chlorobenzaldehyde used in Step B by 2-bromo-4-fluorobenzaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09108983B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-d9f0575f345b40c4a20691a0e3314aa7 |
| Source note | uspto-grants-2015_08 |