Oxalyl chloride → 3-Methoxy-5-isoxazolecarbonyl chloride

Beteiligte Stoffe

Reaktionsschritte

To a solution of 3-methoxyisoxazole-5-carboxylic acid (420 mg, 3 mmol) in THF (15 mL) and DMF (5 drop) was added dropwise oxalyl chloride (650 μL, 7 mmol) at 0° C. The mixture was then stirred at room temperature for 3 hours. The solution was concentrated in vacuo to yield the title compound as a light yellow oil (430 mg).

Herkunft & Nachweise