HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 2-(3-Bromophenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | HCID 18373950 | HCID 18373950 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(3-Bromophenyl)pyridine | HCID 11115506 | — |
Reaction Steps
Under an inert gas atmosphere, 2-bromopyridine and 1.2 equivalents of 3-bromophenylboric acid were subjected to the Suzuki coupling (catalyst: tetrakis(triphenylphosphine)palladium(0), base: 2M sodium carbonate aqueous solution, solvent: ethanol, toluene), to obtain 2-(3′-bromophenyl)pyridine represented by the following formula:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09112154B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-991c9fabe8e54e519c409e73f3ec3e29 |
| Source note | uspto-grants-2015_08 |