HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 86722504, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2,2'-Dibromobiphenyl | HCID 83060 | — |
| Reactant | 9-Phenyl-9H-carbazole-3-boronic acid | HCID 51358450 | — |
| Reactant | HCID 86722500 | HCID 86722500 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86722504 | HCID 86722504 | 56% |
Reaction Steps
Following the procedure for Compound 3, (9-phenyl-9H-carbazol-3-yl)boronic acid (1.84 g, 6.41 mmol), 2,2′-dibromo-1,1′-biphenyl (4.00 g, 12.8 mmol), tetrakis(triphenylphosphine)palladium(0) (0.296 g, 0.257 mmol), Na2CO3 (2.54 g, 24.0 mmol), H2O (24 mL) and THF (40 mL) yielded Compound 9 (1.69 g, 56%) as a colorless solid after flash chromatography (SiO2, 19:1-hexanes: CH2Cl2): confirmed by LCMS (APCI): calculated for C30H20NBr (M+): 474; Found: 474.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09112159B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-4c6e3eb5c46148ea815626c7d777b9dc |
| Source note | uspto-grants-2015_08 |