Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Methyl-3-hexen-2-one → 3-(aminomethyl)-4-isopropyl-6-methylpyridin-2(1H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Methyl-3-hexen-2-one | HCID 5363140 | — |
| 반응물 | 3-(Aminomethyl)-6-methyl-4-propylpyridin-2(1H)-oneacetate | HCID 67124140 | — |
| 생성물 | 3-(aminomethyl)-4-isopropyl-6-methylpyridin-2(1H)-one | HCID 67124337 | — |
반응 단계
The title compound was prepared in the same manner as described for 3-(aminomethyl)-6-methyl-4-propyl-2(1H)-pyridinone (Intermediate 5) using (3E)-5-methyl-3-hexen-2-one (20 g, 137 mmol). LCMS E-S(M+H)=181.1. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.8-11.9 (br s, 1H), 7.86-7.96 (br s, 3H), 6.10 (s, 1H), 3.82-3.86 (m, 2H), 3.02-3.09 (m, 1H), 2.17 (s, 3H), 1.08 (d, 6H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09114141B2 |
| 출처 데이터셋 | uspto-grants-2015_08 |
| ORD ID | ord-75cc395e27714462b97d1e93a895a094 |
| 출처 메모 | uspto-grants-2015_08 |