反应详情

To a solution of dibenzyl 2-hydroxy-2,3-bis(tetrahydro-2H-pyran-4-yl)succinate (2.0 g, 4.15 mmol) in ethanol (50 ml) was added 10% Pd-carbon (300 mg) under a nitrogen atmosphere. The atmosphere in the system was replaced five times with nitrogen gas and was filled with hydrogen gas, and the system was stirred under a hydrogen atmosphere for 24 hr. The catalyst was collected by filtration through Celite pad and was washed with ethanol. The filtrate was concentrated under reduced pressure to give the title compound as a colorless solid (1.2 g, yield 96%).

1. filtrationThe catalyst was collected by filtration through Celite pad
2. washwas washed with ethanol
3. concentrationThe filtrate was concentrated under reduced pressure