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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517059Generated: October 27, 2026

Lithium Hydroxide → 5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acid

https://huagongshe.com/reaction/517059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl esterHCID 57475878—
Product5-(2,2,3,3,3-Pentafluoro-propoxy)-pyridine-2-carboxylic acidHCID 57475877—

Reaction Steps

In a manner analogous to that described in example 17b), the hydrolysis of the 5-(2,2,3,3,3-pentafluoro-propoxy)-pyridine-2-carboxylic acid methyl ester with lithium hydroxide yielded the 5-(2,2,3,3,3-pentafluoro-propoxy)-pyridine-2-carboxylic acid as a white solid. MS (ISP): m/z=271 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115098B2
Source datasetuspto-grants-2015_08
ORD IDord-18647791ec21496b99061747a252763d
Source noteuspto-grants-2015_08