HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-[4-(Trifluoromethyl)phenyl]-1,3-cyclohexanedione → HCID 86732304, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-[4-(Trifluoromethyl)phenyl]-1,3-cyclohexanedione | HCID 599127 | — |
| Reactant | HCID 86732301 | HCID 86732301 | — |
| Product | HCID 86732304 | HCID 86732304 | — |
Reaction Steps
The title compound is prepared in analogy to 1-((4-cyanophenyl)(2-hydroxy-6-oxo-4-(tri-fluoromethyl)cyclohex-1-enyl)methyl)-3-(3-(trifluoromethyl)phenyl)urea (intermediate 12), using 5-(4-(trifluoromethyl)phenyl)cyclohexane-1,3-dione (500 mg, 1.95 mmol) as starting material. Yield: 930 mg; ESI mass spectrum [M+H]+=574, Retention time HPLC: 0.85 min (V011_S01).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115093B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-03d5392d4f084a3c848901834d008f47 |
| Source note | uspto-grants-2015_08 |