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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517213Generated: October 28, 2026

HCID 59145682, compound → HCID 86732332, compound

https://huagongshe.com/reaction/517213

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59145682HCID 59145682—
ReactantHCID 86732331HCID 86732331—
ProductHCID 86732332HCID 86732332—

Reaction Steps

The title compound is prepared in analogy to 1-((4-cyanophenyl)(2-hydroxy-6-oxocyclohex-1-enyl)methyl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)urea (intermediate 44), using 1-(3-fluoro-5-(trifluoromethyl)phenyl)urea (intermediate 43, 630 mg, 1.99 mmol) as starting material. Yield: 378 mg; ESI mass spectrum [M+H]+=448; Retention time HPLC: 1.07 min (Z018_S04).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115093B2
Source datasetuspto-grants-2015_08
ORD IDord-5d882cf97c864b36a06bfe4aa204e1dd
Source noteuspto-grants-2015_08