HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86732332, compound → HCID 86732334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86732332 | HCID 86732332 | — |
| Reactant | HCID 86732333 | HCID 86732333 | — |
| Product | HCID 86732334 | HCID 86732334 | — |
Reaction Steps
The title compound is prepared in analogy to 1-((4-cyanophenyl)(2-methoxy-6-oxocyclohex-1-enyl)methyl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)urea (intermediate 46), using 1-((4-cyanophenyl)(2-hydroxy-6-oxocyclohex-1-enyl)methyl)-3-(3-fluoro-5-(trifluoromethyl)phenyl)urea (intermediate 45, 378 mg, 0.85 mmol) as starting material. Yield: 367 mg; ESI mass spectrum [M+H]+=462; Retention time HPLC: 1.11 min (Z018_S04).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115093B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-d21bfee0a6a54bb690fe9c667a68908d |
| Source note | uspto-grants-2015_08 |