HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86732371, compound → HCID 86732374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86732371 | HCID 86732371 | — |
| Reactant | HCID 86732375 | HCID 86732375 | — |
| Product | HCID 86732374 | HCID 86732374 | — |
Reaction Steps
The title compound is prepared in analogy to 2-(4-(4-cyanophenyl)-2,5-dioxo-1-(3-(tri-fluoromethyl)phenyl)-1,2,5,6,7,8-hexahydroquinazolin-3(4H)-yl)acetic acid (example 32), using (S)-methyl 2-(4-(4-cyanophenyl)-2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-1,2,5,6,7,8-hexahydroquinazolin-3(4H)-yl)acetate (example 31B, 30 mg, 62 μmol) as starting material. Yield: 23 mg; ESI mass spectrum [M+H]+=470; Retention time: 1.09 min (V001—006).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115093B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-867858dd759742b3b5b4953f45cb6afa |
| Source note | uspto-grants-2015_08 |