HCID 77934570, compound → HCID 70869380, compound

HRID 517355Notes

Reaction equation

[C:1]([O:5][C:6]([C:8]([CH3:24])=[CH:9][C:10]1[S:14][C:13]([CH2:15][O:16][Si:17]([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:19])[CH3:18])=[N:12][CH:11]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd]>[C:1]([O:5][C:6]([CH:8]([CH3:24])[CH2:9][C:10]1[S:14][C:13]([CH2:15][O:16][Si:17]([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:18])[CH3:19])=[N:12][CH:11]=1)=[O:7])([CH3:2])([CH3:4])[CH3:3]

Participants

Conditions

Temperature: 50 °C

Procedure

The compound (0.5 g, 1.4 mmol) obtained in step 3 was dissolved in ethanol (20 mL), palladium/carbon (0.1 g) was added, and the mixture was stirred at 50° C. for 20 hours under a hydrogen atmosphere (55 psi). The reaction mixture was filtered, and the solvent was evaporated under reduced pressure to give the title compound (0.3 g).

Workup

filtrationThe reaction mixture was filtered
customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record: ord-d1bbff9e367e4cfa8609dcbf2d513bf2
Source dataset: uspto-grants-2015_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09115107B2

Reaction notes

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