HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Z)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione → (Z)-tert-butyl (1-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)propan-2-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Z)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione | HCID 5878179 | — |
| Reactant | t-Butyl (1-bromopropan-2-yl)carbamate | HCID 22274345 | — |
| Reactant | (Z)-tert-butyl (3-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)propyl)carbamate | HCID 71697170 | — |
| Product | (Z)-tert-butyl (1-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)propan-2-yl)carbamate | HCID 86724392 | 22.5% |
Reaction Steps
The title compound 21b was prepared from compound 2 (260 mg, 1.04 mmol) and tert-butyl (1-bromopropan-2-yl)carbamate (247 mg, 1.04 mmol) in a manner similar to that described for 21a. Yield=22.5%, 95.0 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115122B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-fe4d98ded096494da4effb479bc0665a |
| Source note | uspto-grants-2015_08 |