HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Z)-tert-butyl 2-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetate → (Z)-2-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Z)-tert-butyl 2-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetate | HCID 5958148 | — |
| Reactant | 3-(2-Aminoethyl)-5-(4-ethoxybenzyl)thiazolidine-2,4-dione | HCID 71697071 | — |
| Product | (Z)-2-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetic acid | HCID 6302733 | 93.4% |
Reaction Steps
The title compound 28h was prepared by deprotection of tert-butyl group of compound 28g (300 mg, 0.82 mmol). Deprotection following the procedure of compound 6 gave the title compound 28h as a yellow solid (93.4%, 235 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115122B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-9b65d6db43ce4f728fc7a325a431f427 |
| Source note | uspto-grants-2015_08 |