HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → (Z)-3-benzyl-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (Z)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione | HCID 5878179 | — |
| Reactant | (Z)-5-(4-ethoxybenzylidene)-3-propylthiazolidine-2,4-dione | HCID 71697554 | — |
| Product | (Z)-3-benzyl-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione | HCID 49886692 | — |
Reaction Steps
The title compound 28i was prepared from compound 2 (75 mg, 0.30 mmol), benzyl bromide (39 μL, 0.33 mmol) and potassium carbonate (83 mg, 0.60 mmol) in a manner similar to that described for 28d in 99.6% (101 mg) yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115122B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-6e375dfc74c245068f00c1b7ee4c8c45 |
| Source note | uspto-grants-2015_08 |