HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → (Z)-5-(4-ethoxybenzylidene)-3-(4-nitrobenzyl)thiazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Reactant | (Z)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione | HCID 5878179 | — |
| Reactant | (Z)-5-(4-ethoxybenzylidene)-3-propylthiazolidine-2,4-dione | HCID 71697554 | — |
| Product | (Z)-5-(4-ethoxybenzylidene)-3-(4-nitrobenzyl)thiazolidine-2,4-dione | HCID 1498888 | — |
Reaction Steps
The title compound 28n was prepared from compound 2 (150 mg, 0.60 mmol), p-nitrobenzyl bromide (143 mg, 0.66 mmol) and potassium carbonate (166 mg, 1.20 mmol) in a manner similar to that described for 28d in 99.5% (229 mg) yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115122B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-ce7a9981e6bd4991afa92429fe8a4fab |
| Source note | uspto-grants-2015_08 |