HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Aminoethyl)-5-(4-ethoxybenzyl)thiazolidine-2,4-dione → (Z)-4-((5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)methyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Aminoethyl)-5-(4-ethoxybenzyl)thiazolidine-2,4-dione | HCID 71697071 | — |
| Reactant | (Z)-tert-butyl 4-((5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)methyl)benzoate | HCID 71697763 | — |
| Product | (Z)-4-((5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)methyl)benzoic acid | HCID 56933432 | 97.3% |
Reaction Steps
The title compound 28q was prepared by deprotection of tert-butyl group of compound 28p (100 mg, 0.23 mmol). Deprotection following the procedure of compound 6 gave the title compound 28q as a white solid (85 mg, 97.3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115122B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-9cd36ad9d37345999963616125f3c9f6 |
| Source note | uspto-grants-2015_08 |