Triethylamine → HCID 49609610, compound

Participants

Reaction Conditions

Reaction Steps

5-(Chloromethyl)-1-[4-(trifluoromethyl)phenyl]-1H-tetrazole (79 mg, 0.301 mmol, commercially available from UkrOrgSynthesis, Kiev, Ukraine) and 1-(ethylsulfonyl)piperazine (53.6 mg, 0.301 mmol, Sigma-Aldrich) were dissolved in acetonitrile (1.5 ml). Triethylamine (0.046 ml, 0.331 mmol) was added, and the mixture was heated at 120° C. in a microwave with stirring for 20 min. The reaction mixture was concentrated in vacuo and the residue was purified by high pH MDAP to yield the title compound as a colourless solid (89 mg).

Provenance & Evidence