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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517832Generated: October 30, 2026

Hydrochloric Acid → HCID 59161636, compound

https://huagongshe.com/reaction/517832

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 2-(8-chloro-1,2,3,4-tetrahydro-2-methylpyrido[4,3-b]indol-5-yl)acetateHCID 44159218—
SolventEthanolHCID 702—
ProductHCID 59161636HCID 59161636—

Reaction Conditions

Temperature50 °C

Reaction Steps

A mixture of ethyl 2-(8-chloro-1,2,3,4-tetrahydro-2-methylpyrido[4,3-b]indol-5-yl)acetate and NaOH in ethanol was stirred at 50° C. for 3 h after which it was cooled to RT and neutralized with conc. HCl. The solvent was removed under reduced pressure to obtain crude 2-(8-chloro-1,2,3,4-tetrahydro-2-methylpyrido[4,3-b]indol-5-yl)acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115137B2
Source datasetuspto-grants-2015_08
ORD IDord-d6023756432b4071b1e5feb27245163a
Source noteuspto-grants-2015_08