HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517837Generated: October 30, 2026
Hydrochloric Acid → 2-(1,2,3,4-Tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)acetic acid
https://huagongshe.com/reaction/517837
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 2-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)acetate | HCID 44158421 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(1,2,3,4-Tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)acetic acid | HCID 59161628 | — |
Reaction Steps
A mixture of ethyl 2-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)acetate and NaOH in ethanol was stirred at 50° C. for 3 h after which it was cooled to RT and neutralized with conc. HCl. The solvent was removed under reduced pressure to obtain crude 2-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09115137B2 |
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| Source dataset | uspto-grants-2015_08 |
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| ORD ID | ord-3230f683233841be987dccaa02d42b94 |
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| Source note | uspto-grants-2015_08 |
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