Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 517844Generated: October 29, 2026

Hydrochloric Acid → HCID 59161642, compound

https://huagongshe.com/reaction/517844

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 3-(8-chloro-1,2,3,4-tetrahydro-2-methylpyrido[4,3-b]indol-5-yl)propanoateHCID 44159333—
SolventEthanolHCID 702—
ProductHCID 59161642HCID 59161642—

Reaction Conditions

Temperature50 °C

Reaction Steps

A mixture of ethyl 3-(8-chloro-1,2,3,4-tetrahydro-2-methylpyrido[4,3-b]indol-5-yl)propanoate (CD17) and NaOH in ethanol was stirred at 50° C. for 3 h after which it was cooled to RT and neutralized with conc. HCl. The solvent was removed under reduced pressure to obtain crude 3-(8-chloro-1,2,3,4-tetrahydro-2-methylpyrido[4,3-b]indol-5-yl)propanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115137B2
Source datasetuspto-grants-2015_08
ORD IDord-06d11db1a58d44d3881deace7ba5c621
Source noteuspto-grants-2015_08