Triethylamine → HCID 53329870, compound

Participants

Reaction Steps

1-Methyl-6-(4-(2-(piperidin-4-yl)ethoxy)-3-(trifluoromethyl)phenyl)-1H-[1,2,3]-triazolo[4,5-c]pyridine-4-carbonitrile (50 mg), triethylamine (0.019 ml), and methanesulfonyl chloride (8.99 μl) were combined in dichloromethane (1 ml) and the reaction mixture stirred at room temperature for 3 hours. Washed with water, the organic layer was separated, dried, and blown down to afford crude product. Solid was suspended in methanol and filtered off to afford the title compound (32.5 mg).

Provenance & Evidence