huagongshe.com
HRID518149

反应详情

EQUATION

反应方程式

HRID 518149 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N1CCC(=O)CC1
HCID735900

1-Boc-4-piperidone

C10H17NO3

结构：CC(=O)c1ccc(Br)cc1O
HCID10727403

1-(4-bromo-2-hydroxyphenyl)ethanone

C8H7BrO2

结构：COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CCNCC1)O2
HCID52952093

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1ccc(Br)cc1O2
HCID27281806

tert-Butyl 7-bromo-4-oxo-3,4-dihydro-1'H-spiro[1-benzopyran-2,4'-piperidine]-1'-carboxylate

C18H22BrNO4

PROCEDURE

实验过程

1-(4-Bromo-2-hydroxy-phenyl)ethanone (10.1 g, 47.0 mmol) was coupled with N—BOC-4-piperidone according to the procedure for preparation of Intermediate 1, Step A, giving 7-bromo-4-oxo-spiro[chromane-2,4′-piperidine]-1′-carboxylic acid tert-butyl ester (18 g) as an orange solid.