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HRID518170

反应详情

EQUATION

反应方程式

HRID 518170 的结构方程式

REACTANTS

反应物

2
结构：NOC1CCCCO1
HCID5142091

O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine

C5H11NO2

结构：O=C(O)/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3ccccc3)CC1)O2
HCID52952734

未命名化合物

PRODUCTS

生成物

1
结构：O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3ccccc3)CC1)O2)NOC1CCCCO1
HCID52951279

未命名化合物

PROCEDURE

实验过程

(E)-3-{1′-Benzyl-4-oxo-spiro[chromane-2,4′-piperidine]-6-yl}-acrylic acid (365 mg, 0.97 mmol) was treated with NH2OTHP following the procedure described in Example 1, Step B, giving (E)-3-{1′-benzyl-4-oxo-spiro[chromane-2,4′-piperidine]-6-yl}-N-(tetrahydro-pyran-2-yloxy)-acrylamide (328 mg) as a light yellow oil.