Potassium Carbonate → HCID 118021550, compound

Participants

Reaction Steps

4-methoxybenzene-1-thiol (15.7 g, 0.11 mol), 2-bromoethyl acetate (18.8 g, 0.11 mol), and K2CO3 (46.6 g, 0.34 mol) in acetone (200 mL) were stirred at room temperature for 12 h. Then the mixture was filtered. After CH2Cl2 extractive work up and silica gel chromatography chromatography (PE: EA=1:0-10:1) the title compound (21.1 g, 83.3%) was obtained as a colorless oil. 1H NMR: (CDCl3, 400 MHz) δ 7.40 (dd, J1=6.8 Hz, J2=2.0 Hz, 2H), 6.86 (dd, J1=6.8 Hz, J2=2.0 Hz, 2H), 4.18 (t, J=7.2 Hz, 2H), 3.80 (s, 3H), 3.02 (t, J=7.2 Hz, 2H), 2.03 (s, 3H). LCMS: 139.0 (M−87)+

Provenance & Evidence