Tert-butyl (piperidin-4-ylmethyl)carbamate → HCID 178501181, compound

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Reaction Steps

The title compound was prepared from cis-methyl 4-((E)-2-(4-fluorobenzoylimino)-6-(hydroxymethyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexanecarboxylate and tert-butyl piperidin-4-ylmethylcarbamate using a method analogous to the preparation of cis-methyl 4-((E)-2-(4-fluorobenzoylimino)-6-(piperidin-1-ylmethyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexanecarboxylate (45 mg, 77% yield). MS m/z=622.2 [M+H]. Calc'd for C34H44FN5O5: 621.3.

Provenance & Evidence