HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzoyl isothiocyanate → HCID 178501176, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzoyl isothiocyanate | HCID 14984172 | — |
| Reactant | HCID 178472424 | HCID 178472424 | — |
| Product | HCID 178472392 | HCID 178472392 | — |
| Product | HCID 178501176 | HCID 178501176 | 82% |
Reaction Steps
The title compound was prepared from cis-ethyl 4-(5-amino-2-(2-(benzyloxy)ethoxy)pyridin-4-ylamino)cyclohexanecarboxylate and 3-fluorobenzoyl isothiocyanate using a method analogous to the preparation of cis-methyl 4-((E)-2-(benzoylimino)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)cyclohexanecarboxylate (2.5 g, 82% yield). MS m/z=561.2 [M+H]. Calc'd for C31H33FN4O5: 560.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115127B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-40050412317d43e8afb1c83b58a4c332 |
| Source note | uspto-grants-2015_08 |