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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 518634Generated: October 30, 2026

3-Fluorobenzoyl isothiocyanate → HCID 178501176, compound

https://huagongshe.com/reaction/518634

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluorobenzoyl isothiocyanateHCID 14984172—
ReactantHCID 178472424HCID 178472424—
ProductHCID 178472392HCID 178472392—
ProductHCID 178501176HCID 17850117682%

Reaction Steps

The title compound was prepared from cis-ethyl 4-(5-amino-2-(2-(benzyloxy)ethoxy)pyridin-4-ylamino)cyclohexanecarboxylate and 3-fluorobenzoyl isothiocyanate using a method analogous to the preparation of cis-methyl 4-((E)-2-(benzoylimino)-2,3-dihydro-1H-imidazo[4,5-c]pyridin-1-yl)cyclohexanecarboxylate (2.5 g, 82% yield). MS m/z=561.2 [M+H]. Calc'd for C31H33FN4O5: 560.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115127B2
Source datasetuspto-grants-2015_08
ORD IDord-40050412317d43e8afb1c83b58a4c332
Source noteuspto-grants-2015_08