HCID 178457831, compound → HCID 178525752, compound

HRID 518661Notes

Reaction equation

HRID 518661 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([NH:8][C@@H:9]2[CH2:14][CH2:13][C@H:12]([C:15](NC(C)C)=[O:16])[CH2:11][CH2:10]2)[C:5]([N+:21]([O-:23])=[O:22])=[CH:4][N:3]=1.N[C@@H]1CC[C@H](C(O)=[O:32])CC1>>[Cl:1][C:2]1[CH:7]=[C:6]([NH:8][C@@H:9]2[CH2:10][CH2:11][C@H:12]([C:15]([OH:16])=[O:32])[CH2:13][CH2:14]2)[C:5]([N+:21]([O-:23])=[O:22])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 178457831HCID 178457831, compoundHCID 178511566HCID 178511566, compound

Product 1

HCID 178525752HCID 178525752, compound

Procedure

The compound was made using a procedure analogous to that used in the preparation of cis-4-(2-chloro-5-nitropyridin-4-ylamino)-N-isopropylcyclohexanecarboxamide using cis-4-aminocyclohexanecarboxylic acid.

Sources & evidence

ORD record
ord-00f3465057054d4dbc84ce0efc6ac8ae
Source dataset
uspto-grants-2015_08
Patent number
US09115127B2

Reaction notes

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