Acetic Acid → HCID 178457855, compound

Participants

Reaction Steps

To a solution of cis-N-isopropyl-4-(2-nitro-5-(2-(piperidin-1-yl)ethoxy)phenylamino)cyclohexanecarboxamide (350 mg, 0.809 mmol) in MeOH (4.0 mL) was added AcOH (0.463 mL, 8.09 mmol) and zinc (423 mg, 6.47 mmol), and the mixture was stirred at RT for 1 hour. The mixture was filtered through a pad of Celite® brand filter aid and evaporated to afford cis-4-(2-amino-5-(2-(piperidin-1-yl)ethoxy)phenylamino)-N-isopropylcyclohexanecarboxamide.

Provenance & Evidence