HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178457852, compound → HCID 178457810, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178457852 | HCID 178457852 | — |
| Reactant | HCID 178496069 | HCID 178496069 | — |
| Product | HCID 178457810 | HCID 178457810 | 79% |
Reaction Steps
The title compound was prepared from tert-butyl 2-(4-(5-amino-4-(cis-4-(isopropylcarbamoyl)cyclohexylamino)pyridin-2-yloxy)piperidin-1-yl)acetate using a procedure analogous to that used for (E)-4-fluoro-N-(1-(cis-4-(isopropylcarbamoyl)cyclohexyl)-6-(2-methoxyethoxy)-1H-imidazo[4,5-c]pyridin-2(3H)-ylidene)benzamide. Isolated as an off-white solid (124 mg, 79% yield, last step). M/Z calc'd for C34H45FN6O5: 636.76. found 637 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09115127B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-02723b2d9ab34710a7f2aee231285b0f |
| Source note | uspto-grants-2015_08 |