HCID 178457837, compound → HCID 178457836, compound

Participants

Reaction Steps

To a solution of cis-4-(5-(hydroxymethyl)-2-nitrophenylamino)-N-isopropylcyclohexane-carboxamide (2.0 g, 5.96 mmol) in EtOH (25 mL) was added 10% palladium on carbon (0.635 g, 0.596 mmol). The reaction was stirred under a hydrogen atmosphere (1 atm) at RT. After 3 hours, the reaction mixture was filtered through Celite® brand filter aid and concentrated to afford cis-4-(2-amino-5-(hydroxymethyl)phenylamino)-N-isopropylcyclohexanecarboxamide as a brown oil.

Provenance & Evidence