참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | 4-[4-Nitro-3-(propan-2-yloxy)phenyl]pyridine | HCID 86697963 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 1-Methyl-4-[4-nitro-3-(propan-2-yloxy)phenyl]pyridinium iodide | HCID 86697964 | 97.5% |
반응 단계
A mixture of 7.35 g of 4-[4-nitro-3-(propan-2-yloxy)phenyl]pyridine and 16.1 g of methyl iodide in 150 ml of acetonitrile is heated at 50° C. (bath) for 1 h. 2.5 ml of methyl iodide are added and the heating is continued for 1 h 50. The mixture is then concentrated under vacuum, so as to obtain 11.1 g of 1-methyl-4-[4-nitro-3-(propan-2-yloxy)phenyl]pyridinium iodide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US09115140B2 |
|---|
| 출처 데이터셋 | uspto-grants-2015_08 |
|---|
| ORD ID | ord-e5d5d827fe6f4e26aa166d1f9bf8104c |
|---|
| 출처 메모 | uspto-grants-2015_08 |
|---|
