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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 518925Generated: October 31, 2026

(3S)-2-Carbobenzoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid → (3R)-3-(4-Morpholinylmethyl)-1,2,3,4-tetrahydroisoquinoline

https://huagongshe.com/reaction/518925

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-2-Carbobenzoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic AcidHCID 688307—
ReactantZ-D-Tic-OHHCID 688308—
Product(3R)-3-(4-Morpholinylmethyl)-1,2,3,4-tetrahydroisoquinolineHCID 28596893—

Reaction Steps

The procedure is in accordance with the process of Preparation 1′, replacing the (3S)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid used in Step A by (3R)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09115159B2
Source datasetuspto-grants-2015_08
ORD IDord-e144695b03ad425b8e25384cb460ebf8
Source noteuspto-grants-2015_08