Hydrazine → HCID 86727430, compound

Participants

Reaction Steps

To a solution of 7-fluoro-6-nitro-2H-benzo[b][1,4]oxazine-3(4H)-thione (Example #56, Step D, 1.0 g, 3.05 mmol) in MeOH (10 mL) was added hydrazine (55% wt, 0.2 mL, 3.4 mmol) at ambient temperature and the reaction mixture was stirred at ambient temperature overnight. The precipitate was collected by filtration to give 7-fluoro-4-methyl-6-nitro-2,10-dihydro-9-oxa-1,2,4a-triaza-phenanthren-3-one (0.63 g, 74%) as an orange solid. LC/MS (Table 1, Method 2) Rt=0.884 min; MS m/z: 281 [M+H]+

Provenance & Evidence