Trifluoroacetic acid → HCID 86727469, compound

Participants

Reaction Steps

A solution of tert-butyl 4-(1-methyl-2-oxo-8-phenyl-1,2,3,5-tetrahydrobenzo[5,6][1,4]oxazino[3,4-c][1,2,4]triazin-9-yl)piperidine-1-carboxylate (0.020 g, 0.042 mmol) in DCM (6 mL) and TFA (1 mL) was stirred at ambient temperature for 1.5 h. The solvent was removed in vacuo to give 1-methyl-8-phenyl-9-(piperidin-4-yl)-3,5-dihydrobenzo[5,6][1,4]oxazino[3,4-c][1,2,4]triazin-2(1H)-one trifluoroacetic acid (0.016 g, 78%) as a pale yellow solid. LC/MS (Table 1, Method 5) Rt=2.314 min.; MS m/z: 377 [M+H]+.

Provenance & Evidence